Biotechnology startups in San Francisco Bay Area

Edison Scientific

San Francisco

Edison Scientific, spun out from FutureHouse in 2025, accelerates scientific discovery by building and commercializing AI agents for science, pursuing an AI Scientist to scale autonomous research and tackle challenges such as drug developme

Plasmidsaurus

South San Francisco

Plasmidsaurus accelerates cures and a healthier planet by boosting productivity of scientists using DNA tools through 10 24/7 labs, serving Nobel Prize winners, with rapid DNA-sample logistics under 12 hours and a goal to save 4 million hou

Pilgrim

Redwood City

Pilgrim develops, validates, and deploys battlefield-ready biotechnology, turning breakthrough science into decisive capabilities for operators at the edge.

Inductive Bio

San Francisco

Inductive Bio uses data, machine learning, software, and domain expertise to rapidly solve ADMET problems with speed and precision, streamlining ADMET workflows as a focused provider in the ADMET problem space.

BillionToOne

Menlo Park

BillionToOne is a molecular diagnostics company focused on prenatal and oncology testing, backed by Y Combinator and $200M+ funding. It developed a DNA counter that raises cell-free DNA resolution, enabling single-gene disorder detection fr

ZBiotics

San Francisco

ZBiotics is a biotechnology company developing genetically engineered probiotics, the world’s first such products, using patented technology to create a new product category and advance the public discussion of GMO while improving daily lif

Pendulum™

San Francisco

Pendulum Therapeutics is the leading innovator in microbiome science, delivering research based probiotic formulations to support metabolic health. The company leverages cutting-edge research and strong intellectual property to bring effective, science-backed solutions to consumers worldwide. Pendulum Akkermansia was the first novel species to be brought to the probiotics market in more than 50 years. The first and only probiotic in the world clinically proven to lower A1C and blood glucose in people with type 2 diabetes, Akkermansia stimulates natural GLP-1 production.

General Proximity

San Francisco

**General Proximity** The next generation of induced-proximity medicines. Active biotech drug-discovery San Francisco **Founders** Armand Cognetta Founder Armand completed his PhD in Chemical Biology at the Scripps Research Institute un

Neon Health

San Francisco

Neon Health automates patient access workflows for pharma companies, streamlining benefit verifications, prior authorizations, financial assistance enrollment, onboarding, and adherence management to accelerate access to life-saving treatme

Bindwell

San Francisco

Bindwell uses AI to discover new pesticides, replacing slow lab work and accelerating discovery by 100×. The company is a small team of Caltech and Wolfram Research alumni with drug-discovery ML experience, aiming to rebuild agrochemical R&

Auricle

Mountain View

Auricle develops an implantable neurostimulation device to restore hearing for patients who no longer benefit from hearing aids but are not ready for cochlear implants, using a reversible, minimally invasive approach that preserves residual

Diffuse Bio

San Carlos

Diffuse builds generative AI for protein design, with coverage from The New York Times and NBC News; it has produced the first crystal structures of AI-designed proteins and diffusion models for structure and sequence generation.

Beeflow

San Francisco

Beeflow develops nature-based solutions to improve pollination in agriculture by combining ecological science with technology; it operates at the intersection of nature-based approaches and agricultural innovation to advance pollination pra

Mekonos

San Francisco

Mekonos is a Silicon Valley Venture-backed Life Sciences company — creating a proprietary cell-engineering platform based on scalable silicon technology for our partners engaged in cell & gene therapies and cell line development.

Verge Genomics

San Francisco

Verge Genomics uses AI and human tissue data in its CONVERGE platform to map disease biology, identify targets, and de-risk drug development, with two drugs in clinical trials, 282 targets discovered, and partnerships worth $1.6B.

Principia Biopharma

South San Francisco

Sanofi is a global biopharma company focused on prescription drugs, vaccines, and treatments for chronic, rare, and infectious diseases.

Human Longevity

South San Francisco

Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.

Centivax

South San Francisco

Smash the mutants

Capacity Bio

Palo Alto

The Mitophagy Company