Startups in California

Spruce

California

Spruce aims to empower users to own their identity and data across all digital interactions, emphasizing user control over personal information and a shift in how identity and data are managed online.

Freemodel

California

Freemodel is a leader in pre-sales home renovation, helping agents sell homes faster and for more with no upfront payments; it is paid at escrow when the home sells.

Uplimit

California

Uplimit provides an AI-powered platform for organizations to create, manage, and deliver learning programs, built by education experts. It serves clients such as Kraft Heinz, GE HealthCare, Databricks, and Procore, and is backed by OpenAI/D

Drivetrain

California

Drivetrain is a business planning and decision-making platform that helps businesses scale and achieve their targets predictably, enabling scalable, predictable outcomes for customers.

Coram AI

California

Coram AI builds Physical AI by turning cameras, sensors, and access systems into AI Safety Agents that protect people and optimize operations. Backed by $30M from Battery Ventures and 8VC, it serves Fortune 500s across industries with safet

Bedrock Ocean Exploration

California

The company is a vertically-integrated ocean exploration firm that develops proprietary robotics and software, aiming to rapidly and cost-effectively map and explore the Earth's oceans at a scale not possible with current technology.

Home365

California

Home365 is a property management and real estate investment company that leverages technology, AI, and data to transform owning and renting real estate, aiming to reduce the risks and unknowns of rental property ownership and deliver predic

Virtualitics

California

Virtualitics brands itself as the Mission AI Company, a fast-growing startup built on a decade of Caltech research in partnership with NASA/JPL, focusing on mission readiness and operational efficiencies.

Weee!

California

Weee! is a leading Asian e-grocer in the U.S. delivering over 10,000 locally sourced and hard-to-find goods from around the globe, leveraging social e-commerce and proprietary forecasting; founded in 2015 in SF Bay Area, it has raised over

Boxbot

California

Boxbot transforms conveyors into intelligent, three-dimensional package handling systems that store, sort, and sequence high-throughput, size-agnostic payloads in a compact footprint, with a mission to reduce last-mile delivery costs across

Neptune.ai

California

Provides monitoring and debugging tools for machine learning training, tracking thousands of per-layer metrics (losses, gradients, activations) at any scale with real-time, lag-free visualization to drill into logs, quickly debug issues, an

Mashgin

California

Mashgin develops automated checkout technology using 3D computer vision and deep learning, the world’s only system of its kind, to reduce friction at checkout, with deployments in 1,500+ locations serving brands like Circle K and Aramark.

THE/STUDIO

California

The company aims to build the world’s largest customer-centric digital factory and a marketplace linking leading brands with top-tier manufacturers, empowering creators to bring products to life and educating customers on the transformative

The Shift Network

California

The Shift Network is a group founded in 2010 that promotes transformation through learning and aims to catalyze a shift of consciousness toward sustainable, peaceful, healthy, and prosperous society, reinforced by its slogan “Shift your wor

Hilbert's AI

California

The AI-native B2C Growth Infrastructure.

Hestus

California

Hestus develops AI-powered CAD software to accelerate hardware development. Led by ex-Cruise engineers Kevin Chu and Sohrab Haghighat, a two-time YC founder who built SpaceRyde, the startup is fast-growing and leverages deep robotics and ae

Duranium

California

Duranium develops carbon-neutral, lightweight metals in the United States, using existing chlorination/electrolytic tech and a molten-materials process to convert metal-production byproducts into feedstocks and high-value coproducts. Based

Apolink

California

Apolink is developing the world’s most interoperable low Earth orbit satellite relay network, using a hybrid RF and optical inter-satellite links architecture to deliver real-time, continuous connectivity for satellite operators across indu

Hippocratic AI

California

Hippocratic AI develops a safety-focused healthcare LLM to improve accessibility and outcomes by applying deep medical expertise; led by CEO Munjal Shah, it has $278 million in funding from investors and six health systems.

Qualified Health

California

Qualified Health provides a healthcare-native AI platform for health systems to deploy safe, scalable AI, emphasizing safety and trust as prerequisites for scaling. Serving 400,000 users across health systems nationwide, it aims to deliver

Windfall Bio

California

Windfall Bio has developed the first-ever solution to capture and transform methane emissions into organic fertilizer. This nature-based solution harnesses methane-eating microbes to transform methane from any source into valuable outputs.

Swif.ai

California

Swif.ai acts as the governance layer that enables companies to deploy AI safely across organizations, emphasizing governance and security with SOC 2 Type II compliance.

Voyage Foods

California

The company provides sustainable, scalable versions of beloved foods that are nearly identical in taste and nutrition to traditional foods, with a mission to protect individual health and the planet.

DataHub

California

DataHub offers an enterprise-grade metadata platform and open-source and managed cloud offerings to deploy AI in production, backed by LinkedIn, and supports a community of over 13,000 practitioners, positioning itself as a unique solution

Bito

California

Bito provides AI-powered code assistance integrated with GitHub, GitLab, and Bitbucket to deliver organization-wide codebase context, while not storing code or training models; SOC 2 Type II certified and free to start with no credit card r

Seraphic Security

California

Seraphic provides Browser Security to secure access to SaaS and web apps from managed or personal devices, with patented technology, enabling VDI/VPN-free access and supporting SaaS apps. It raised a $29M Series A in Jan 2025 with CrowdStri

Reviving Mind

California

Reviving Mind is a telehealth company reversing chronic illnesses in older adults by tackling loneliness, blending social wellbeing with medical care to improve senior health. Led by multiple-time Y Combinator founders, it develops automati

Onehouse

California

Onehouse is a pioneer in open data lakehouse technology, enabling enterprises to deploy a world-class data lakehouse in minutes. Its platform, built on Apache Hudi and Apache XTable (Incubating), eliminates lock-in and guarantees interopera

Olympian Motors

California

Olympian Motors is a new, disruptive automaker in the United States that operates a fully fabless, asset-light production model with no CAPEX, no in-house factory, and no upfront R&D, making it a notable entrant in the automotive market.

Pangea

California

Pangea offers an AI Guardrail Platform that secures AI applications and workforce usage, covers eight OWASP Top Ten Risks for LLMs, and lets security and product teams deploy guardrails via gateways or in apps with a few lines of code.

Lawmatics

California

Lawmatics is the #1 growth platform for law firms, offering an integrated suite of client intake, CRM, marketing automation, and performance analytics to help firms win more business and become more profitable. Founded in 2017 and based in

Brightline

California

Brightline is a family-focused mental health platform providing virtual therapy, psychiatry, and coaching for kids and teens nationwide, offering fast, personalized, evidence-based care and tools to track progress and book appointments.

Brella

California

Brella aims to transform childcare with a flexible, accessible, and friendly center, addressing gaps for parents, children, and teachers. It is expanding across multiple facilities (197494347, 196494348, 198021222, 198021221, 198020953, 198

Ansa Biotechnologies

California

Ansa Biotechnologies develops DNA synthesis technology to accelerate innovation in medicine, agriculture, and biotechnology, aiming to empower scientists to create solutions for health and sustainability. Careers are listed on its website;

Alkira

California

Alkira delivers on-demand network infrastructure via a network infrastructure-as-a-service platform, enabling organizations to own and operate networks with agility while integrating security, visibility, and governance. It connects users,

Matroid

California

Matroid operates in AI and computer vision, offering a Studio to create and deploy Detectors for video analysis, enabling real-time alerts from live streams or search of recorded video, and aiming to reduce costs while improving safety and

Tigera

California

Tigera provides Calico, a unified network security and observability platform to prevent, detect and mitigate security breaches in Kubernetes clusters. We are also the creator and maintainer of Calico Open Source, the most widely adopted co

Triparound

California

Triparound is a B2B travel tech SaaS that provides a guest experience platform for hotels, resorts, and vacation rentals, helping streamline operations, boost guest satisfaction, and drive ancillary revenue worldwide.

Databook

California

Databook is a leader in agentic AI for enterprise GTM teams, helping them win 2.5x larger deals and shorten deal cycles by 1.5x; top buyers like Salesforce, Microsoft, and Databricks rely on its award-winning platform.

Saara

California

Saara is an eCommerce technology company that uses artificial intelligence to help online brands reduce the economic and environmental impact of product returns.

Lilac

California

Lilac engineers scalable lithium extraction technology based on ion exchange to enable faster, cheaper, cleaner production. It designs and develops commercial projects across various lithium sources, aiming to make lithium supply a non-issu

Nutcracker Therapeutics

California

Nutcracker Therapeutics is an RNA therapeutics company that combines advanced engineering with high-precision biosynthesis to deploy a complete RNA platform. It maintains a wholly owned pipeline and collaborates with investigators worldwide

Pyka

California

Pyka develops autonomous electric aircraft and a complete propulsion and avionics ecosystem for cargo transport and crop protection, delivering scalable solutions across four continents with industry-first FAA approvals and a focus on safet

Canopy

California

Canopy is an AI-native platform for oncology practices that enables continuous, between-visit care, extending support beyond the clinic to improve patient outcomes and triage efficiency while generating meaningful revenue from care.

Xona Space Systems

California

Xona is building the most accurate and secure positioning, navigation, and timing (PNT) system on Earth, delivering a highly precise PNT solution and aiming to set a new standard in PNT technology.

BigHat Biosciences

California

BigHat is a biotech company accelerating the design of next-generation antibody therapeutics to improve human health, positioning itself at the forefront of antibody design; it is backed by a notable group of investors.

Workiz

California

Workiz, founded in 2015 by locksmiths in San Diego, offers field service management software; touted as the #1 FSM platform and AI leader, trusted by over 120,000 service professionals and built by field service pros for field service pros.

ZEDEDA

California

ZEDEDA provides cloud-native edge management and orchestration for distributed edge infrastructure and applications, aiming to make edge computing effortless, open, and secure by extending the cloud experience to the edge, with an open part

LeoLabs

California

LeoLabs is a leading mission partner for persistent Orbital Intelligence, enabling military, government, and commercial space operators to detect, track, characterize, and respond to space threats with a proliferated radar network and AI-po

Apex.AI

California

Apex.AI develops safety-certified, scalable software for mobility and software-defined vehicles, building on ROS and Eclipse iceoryx with a proprietary process to meet top functional-safety standards. Founded in 2017, HQ Palo Alto, with off

HALO Precision Diagnostics

California

HALO Precision Diagnostics focuses on early detection of leading causes of death using precision diagnostics, delivering rapid, precise, actionable results to enable life-changing treatments for patients, optimizing its solutions on the HAL

Avicena Tech

California

The company operates in the semiconductor interconnects sector, with its core area identified as semiconductor interconnects within the broader semiconductor industry.

Terray Therapeutics

California

Terray is a biotechnology company that discovers and develops small molecule therapeutics by integrating ultra-high throughput experimentation, generative AI, biology, chemistry, automation and nanotechnology to create iterative, data-rich

ClearNote Health

California

ClearNote Health is a US-based cancer-detection company using a proprietary epigenomic platform that blends biology and AI to identify DNA changes signaling cancer; its CLIA- and CAP-accredited lab in San Diego, California, serves the San F

Doxel

California

Doxel offers the only complete automated construction progress tracking solution, contextualizing site, BIM, schedule, and budget data to provide an objective current status and forecast, with machine-generated risk insights to prevent cost

Tonkean

California

Tonkean provides an AI-powered process orchestration platform for enterprise internal service teams, such as procurement and legal, helping Fortune 500 companies automate workflows. It is positioned as the first-of-its-kind platform and the

BeeHero

California

BeeHero leverages machine learning and low-cost sensors to enable precision pollination, boosting yields by 30% and covering 70% of major crops; it operates globally and maintains the largest database of bees and pollination, with traction

Antora Energy

California

Antora builds and deploys factory-built thermal energy storage systems in the United States to power always-on industrial operations with abundant, low-cost, clean energy. Its mission is to bring this solution to industrial facilities world

Seyond

California

Seyond is a leading global provider of image-grade LiDAR technology, enabling safer, smarter mobility. From Silicon Valley, it serves automotive, intelligent transportation, robotics and industrial automation worldwide, with partners such a

GITAI

California

GITAI is a space robotics startup aiming to provide safe, affordable space labor. It pursues Lunar and Matian development, building habitats and mining resources, to enable humanity’s expansion, and claims proven technology demonstrated in