309 AI/ML companies in San Francisco.
By the Numbers
Funding
Cognition
San Francisco
The company is an applied AI lab that builds end-to-end software agents and collaborative AI teammates, enabling engineers to focus on more interesting problems and empowering teams to pursue ambitious goals; it markets Devin as the first A
Poolside
Poolside is building the world's most capable AI for software development, focusing on distributed training and inference of large language models for source code generation, with a mission to unlock developers' potential through AI for sof
The Bot Company
The Bot Company builds household robots to give people back time, pursuing in-house AI, software and hardware. It plans to deploy millions at home before expanding, and has raised $300M, including a $150M Greenoaks-led round, valuing the co
Decagon
Decagon is a leading conversational AI platform delivering concierge customer experiences with AI agents across chat, email, and voice in any language. It serves brands like Hertz, Eventbrite, Duolingo, and Oura and is backed by Accel and A
Decart
Decart provides efficient systems-level AI infrastructure that dramatically accelerates training and inference of the largest generative models, enabling Decart to train its own foundational interactive models and offer real-time access to
LMArena
LMArena, created by UC Berkeley researchers, is an open platform for accessing and comparing leading AI models, where users rate responses and help build a public, real-world leaderboard to increase transparency in AI progress.
Listen Labs
Listen is an autonomous market researcher that uses AI to design interviews, recruit participants, and analyze responses, delivering insights in hours rather than weeks, 24/7. Trusted by Google, Microsoft, SKIMS, Nestlé, and hundreds of ent
Bretton AI
Bretton AI (formerly Greenlite AI) builds AI agents for financial crime compliance, helping banks and fintechs automate AML and KYC work.
David AI
David AI builds audio datasets through R&D; founded in 2024 by former Scale AI engineers, it counts FAANGs and AI labs among customers and raised a $50M Series B from Meritech, NVIDIA and others, achieving seven-figure revenue in six months
Edison Scientific
Edison Scientific, spun out from FutureHouse in 2025, accelerates scientific discovery by building and commercializing AI agents for science, pursuing an AI Scientist to scale autonomous research and tackle challenges such as drug developme
Stand Insurance
The company protects and insures homes against wildfire and hurricane risks by applying physics and AI to model true property risk, enabling more homes to be insurable.
Artisan
Artisan builds AI employees called Artisans and aims to replace the SaaS stack with a single integrated platform, starting with outbound sales; it consolidates every sales SaaS into one platform, framing it as next Industrial Revolution and
Noon
Noon (formerly Weaver) is an AI-native product design tool that links design and code so product teams can go from idea to shipped interface.
Counsel Health
Counsel is building an AI-driven healthcare practice to scale care delivery and provide rapid, personalized medical advice, leveraging partnerships with leading healthcare organizations and collaborative clinician–AI models; founded 2023, r
Delve
Delve is an AI-native compliance company helping 700+ fast-growing firms achieve SOC 2, HIPAA, ISO, GDPR, and other standards in days, not months; trusted by Lovable, Bland, and Wispr Flow, and building an AI-native platform to automate com
E2B
E2B is a Series A startup building the next hyperscaler for AI agents. It has seven figure revenue and has raised over $32M from investors including Insight Partners, serving Perplexity, Hugging Face, Manus, and Groq in San Francisco and Pr
Casca
Casca is building AGI for banking, replacing legacy systems with AI-native tech that automates 90% of manual work. It emphasizes responsible AI with human-in-the-loop monitoring and is backed by Y Combinator, Peterson Ventures, The Sarah Sm
Alembic
Alembic provides causation analytics on proprietary data at scale, answering questions generic AI cannot. It serves Fortune 500 clients including Nvidia, Delta Air Lines, Mars; it operates one of the world's fastest private supercomputers a
Wordware
Wordware offers a web-hosted IDE that lets non-technical domain experts collaborate with AI engineers to build task-specific AI agents, treating prompting as a programming language for natural language programming and agent orchestration.
AfterQuery
AfterQuery builds datasets and experimentation to advance frontier LLM and AI-agent workflows, constructing complex data-infrastructure for agentic and hard-reasoning tasks. It partners with five AI labs and is YC's infrastructure partner, led by teams from top banks and quant firms.
Judgment Labs
Judgment Labs provides infrastructure for Agent Behavior Monitoring (ABM) to observe post-deployment autonomous-agent behavior at scale, serving hundreds of teams. It has raised over $30 million from notable investors and positioned as a le
FurtherAI
FurtherAI is a domain-specific AI company for the insurance industry, helping insurers, reinsurers, MGAs, and brokers drive better decisions at scale. Backed by a16z, Y Combinator, Nexus, and Converge, it supports customers writing over $15
Unify
Unify is an AI-first go-to-market platform that treats growth as a science, powering pipeline for leading teams such as Airwallex, Cursor, Perplexity, Together AI, and Guru. Founded Jan 17, 2023 by Austin Hughes and Connor Heggie, with a Li
Moonlake
The company builds multimodal reasoning models, developing AI systems that can reason across multiple modalities and integrate diverse data types. This focus positions it in a technically advanced area of AI development.
Indent
Indent is a platform for large engineering teams, used for incident response, code review, and data analysis with minimal setup. It provides a cloud AI software engineer that handles the entire job, including real-world tasks like analyzing
Mem0
Mem0 provides a universal, self-improving memory layer for LLM applications, enabling personalised AI experiences while reducing costs and boosting user delight. It markets itself as "The memory layer for Personalized AI."
Sauron
Sauron provides residential security via autonomous robots and cars, led by alumni of Zipline, Tesla, Apple, and Google. Incubated by Kevin Hartz and Atomic, it has raised rounds totaling at least $40M from investors including A*, 8VC, and
Alex (formerly Apriora)
Alex AI builds the future of hiring with an autonomous recruiter that conducts real-time video interviews, asking employer-selected or job-based questions and personalized follow-ups to speed hires and improve signals; it supports thousands
Automat
Automat is a generative AI platform that creates and scales end-to-end automations, redefining Enterprise AI Agents, RPA, and Intelligent Document Processing; it serves some of the world's largest companies and claims 10x speed and lower co
Archil
Archil connects AI applications to data resources, including model training, agents, and sandboxes, enabling data access for AI development and experimentation. It positions itself as the connector between AI tools and the data they require
Browser Use
The company specializes in animating web agents, bringing them to life as living entities on the web.
ComfyUI
ComfyUI is a San Francisco-based, open-source, node-based engine for generating visual AI content, billed as the world’s leading visual AI platform with a modular system and a community of millions of users, 60k GitHub stars, and thousands
Phonely
Phonely develops voice AI technology to improve customer support and enable doctors to see more patients, while reducing hold times. It positions itself as a leader in intelligent, scalable customer communication and aims to redefine how bu
Eigen
Eigen is building a consumer social company focused on peer-like connections rather than an assistant, aiming to redefine social experience with intuitive product design and human-centered interactions.
Hark
Hark builds an end-to-end AI automation system—from workflow ingestion to production monitoring—plus services that accelerate deployment 10x; founded by Obaid Khan and Tim Lee, bringing operator credibility from Motive, Miso Media, and Code
Simple AI
Simple AI builds enterprise-grade voice AI agents to automate customer conversations at scale, handling millions of calls for brands like Doordash, xAI, and Omaha Steaks. Backed by Y Combinator and notable investors, the lean startup aims t
Tamarind Bio
Tamarind provides access to AI-powered drug discovery for scientists, used by thousands from pharma, biotech, and academia, serving a broad, cross-industry research community.
Mandolin
Mandolin is building last-mile delivery infrastructure to speed development and delivery of cutting-edge drugs (cell/gene therapies, biologics), aiming to extend healthy lifespans by shortening time to patient access; backed by SignalFire,
ZeroPath
ZeroPath, founded by security researchers formerly from Tesla and Google, helps developers ship secure code faster with a developer-friendly solution that changes how teams approach application security.
Dedalus Labs
Dedalus Labs provides an MCP gateway and servers, unifying the AI agents ecosystem with a drop-in API. It enables users to go from idea to production in a single click, mixing models from any vendor with MCP marketplace tools.
Cogent Security
Cogent develops AI-powered vulnerability management solutions for enterprises, aiming to create an AI Taskforce for Vulnerability Management to boost efficiency and accelerate risk reduction. It is trusted by brands and led by executives fr
Omen.ai
Omen AI develops industrial diagnostics and the Digital Mechanic, an intelligent diagnostic layer for industrial machines. Backed by leading investors, its technology has been deployed with Fortune 500 fleets and the company is scaling rapi
Proximal
Proximal builds realistic training environments that mirror software engineering work and collaborates with frontier labs and enterprises to simulate complex tasks, helping clients train and adapt the next generation of coding agents.
Crucibl
Onyx
Onyx is an open-source AI assistant that aggregates company documents, apps, and people (Slack, Google Drive, Confluence, GitHub) to provide immediate answers from a single interface, with 24/7 availability and customizable assistants; foun
Lemon Slice
Lemon Slice is building a video foundation model for human motion and emotion, backed by a $6M seed from Y Combinator, Matrix Partners, The Chainsmokers and others; it has generated 1M+ videos and trains models as part of GenAI strategy.
Hamilton AI
Hamilton AI is building the operating system for business aviation, replacing fragmented communications with a fully integrated platform that uses AI to support scheduling, trip management, and operational decision-making, delivering real-t
Known Dating
Known positions itself as a generational companion for dating, friendships, and networking, supporting connections across diverse contexts and accompanying people through the full spectrum of relationships.
Dosu
Dosu makes engineering knowledge accessible to developers, empowering the community with AI-driven tools. A small San Francisco-based team backed by over $9M in funding, its software is used on thousands of open-source GitHub repos and supp
Highlight
The company markets itself as an on-screen personal assistant and aims to make users 10x faster at their jobs, positioning its product as a tool to streamline work and speed up daily tasks through on-screen assistance.
Unsiloed AI
Unsiloed AI provides production-grade APIs that ingest, parse, structure, and split documents into Markdown and JSON, preserving hierarchy and domain-specific context for Finance, Legal, and Healthcare workflows, enabling reliable AI/LLM us
Subhub
SubHub automates construction estimating by converting blueprints into estimator-ready takeoffs, reducing a 3+ month manual process to days.
Sphinx
Sphinx builds AI analysts that operate inside browsers and internal systems. Its agents, used by banks and fintechs across the United States, Canada, Europe, and Latin America, handle 90% of manual work and cut costs by 4x.
Altara
Altara is a San Francisco startup building an AI co-scientist for the physical world to accelerate breakthroughs in semiconductors, batteries, materials, chemicals, and aerospace, aiming to define a new AI-for-science category; backed by Gr
Overtone
Overtone, led by the founder and former CEO of Hinge, is building a new kind of dating service to help daters find someone who truly resonates. It has an office in New York City that emphasizes in-person collaboration.
Vmax
Vmax is an applied research lab at the frontier of reinforcement learning, developing techniques to leverage RL with Large Language Models.
Runloop
Runloop focuses on infrastructure and orchestration for AI agents, aiming to power the Agentic Web. With a small team of engineers formerly from Google and Stripe, it tackles productionizing AI for software engineering at scale.
Abacus
Abacus builds AI agents to automate tedious accounting workflows, redefining how accounting firms operate. It serves large enterprise clients, generates meaningful revenue, and is led by a two-person founding team backed by top-tier investo
Statics
Statics is building Context OS for AI agents to optimize context and improve LLM performance. Backed by Tier 1 VCs, including a16z, it works with a portion of Forbes AI 50 and is an early-stage company led by Johnny Wang.
Lumena
Lumena empowers domain experts to build AI-powered enterprise applications, enabling humans and AI to collaborate across systems such as Salesforce, NetSuite, and HubSpot. Its design partners include mid-market and enterprise companies in f
Onos Health
Onos Health is a San Francisco-based early-stage startup building an AI-powered platform to reduce waste in U.S. healthcare spending by aligning providers and payers, with a $6M seed round, live partnerships with major health plans, and exp
Assert
Assert.dev is building a modern code-review interface for AI-enabled development, guided by the slogan "Code is meant to be run, not read." It operates the assert.dev website and aims to modernize code review for the AI era.
XOXO AI
XOXO AI is a stealth research lab building consumer social AI that predicts user needs and fulfills them without prompts, aiming to democratize intelligent interfaces. It is assembling engineers, designers, and researchers to lead the next
Muro
Muro AI provides AI agents for Architectural, Engineering and Construction firms to automate pre-construction activities such as scoping and bid leveling, aiming to transform $2 trillion construction industry; led by CEO Kalyan Gautham, CTO
Variant
Variant is building a code generation platform that aims to bring generative creativity to design tools, and it is well-capitalized and backed by notable investors.
Deepnight
Deepnight develops a low-light camera embedded with an AI model to enable robots, drones, autonomous vehicles, and head-mounted displays to operate in total darkness, delivering enhanced vision in extreme lighting conditions.
Crewline AI
Crewline AI retrofits heavy equipment with plug-and-play autonomy and teleoperation kits, enabling autonomous or teleoperated operation on real construction sites across any vehicle. Its hybrid autonomy-plus-human-in-the-loop approach suppo
Mesa
Mesa builds next-generation developer tools focused on code review, quality, and productivity. Backed by Innovation Endeavors, Essence VC, South Park Commons, and leaders like Thomas Wolf of Hugging Face, it aims to reshape software develop
Roger Healthcare
Roger uses generative AI to alleviate staffing shortages in home health care, with full deployment at agencies serving tens of thousands of patients daily.
Phinity
Phinity creates AI training environments and distills expert engineering workflows into reinforcement learning environments across hardware, AI, mechanics, and manufacturing to enable AI to master engineering skills that reshape civilizatio
Radical Healthcare
Radical, a San Francisco-based company, aims to give every cancer patient access to the world’s best oncologist and holds exclusive access to a 400+ million-note, 8 million-record cancer dataset, backed by an elite advisory board and top-ti
Continue
Continue is a San Francisco–based startup (YC S23) backed by Heavybit and notable angels; Siemens is rolling out Continue, which has 26k+ GitHub stars and 2M+ downloads, and focuses on amplifying developers at the intersection of AI and dev
Vals AI
Vals AI is building the standard for evaluating real-world performance of large language models, originating from Stanford NLP evaluation research. Its $5 million seed round and its evaluations are used by major foundation model labs, enter
Pax
Pax is the first AI-powered duty drawback broker that automates and optimizes duty refunds, delivering 15% more refunds and a 99% reduction in processing time, founded by experts from Charter Brokerage, MIT, Google, Amazon, and Flexport.
Klarity
Klarity Health provides high-quality, worry-free and low-cost telehealth services, ensuring comprehensive care is within reach. Whether you're seeking mental health support, weight management, or counseling and therapy, Klarity is your trusted marketplace for health and well-being. We have facilitated over 350,000 telehealth visits and are trusted by 80,000+ patients and 400+ medical specialists. Check out our 5-star ratings: https://www.reviews.io/company-reviews/store/helloklarity
Thunder Compute
Thunder Compute, backed by Y Combinator, raised a $4.5 million seed round and aims to revolutionize GPU utilization, with over $500,000 in revenue in six months and rapid scaling.
Willow
Willow is building a voice operating system that enables computer control via voice, writes for you today, takes actions for you tomorrow, and anticipates needs before you ask. It has Uber adoption; backed by Y Combinator and Box Group.
Remy
Remy builds autonomous AI product teams, beginning with design agents, to provide a 24/7 visual exploration and brainstorming partner for software teams, with the aim of becoming an autonomous teammate that ideates, designs, and ships softw
Latent
Latent develops AI-driven medical intelligence software to optimize hospital and clinic workflows, speed medication access for patients, and boost provider revenues, collaborating with major healthcare systems to expand fast, affordable pro
Theta
Theta translates real-world workspaces into simulation environments and trains expert-level agents that deeply understand those environments.
Weave
Weave applies machine learning to engineering data, scanning every pull request to estimate its duration and evaluate review quality and work type, enabling teams to gain visibility and improve predictability in software delivery.
Ivo
Ivo develops generative AI products for legal teams and an AI-native platform that automates contract review and other legal work, helping teams reduce time, effort, and cost and accelerate time-to-close.
Fay Nutrition
Fay is a healthtech company using AI-powered preventative care to empower people and care teams to avert deterioration, with thousands achieving measurable improvements and $75 million raised from notable investors including General Catalys
11x
11x builds fully autonomous digital workers that automate specific jobs end-to-end, aiming to sell work, not software; a pioneer in digital workers with hundreds of customers including Brex, Otter AI, and Hasura, and millions in revenue in
Fieldguide
Fieldguide offers a vertical AI platform for assurance and advisory firms, founded by ex-Big Four practitioners and tech leaders; headquartered in San Francisco, remote-first, backed by notable investors, trusted by top CPA firms to improve
MERGE
Merge is a leading provider of customer-facing integrations and agent tools for frontier LLMs, serving thousands of customers including Fortune 500s and B2B SaaS firms, with offices in San Francisco, New York, and Berlin.
Supergood
Supergood combines observability data with human-in-the-loop code generation to create new integrations and fix existing ones.
DeepTrust
DeepTrust builds the trust layer of the internet by securing live voice and video calls across platforms and automating social-engineering detection and response, providing just-in-time assistance to boost productivity, security, and compli
ScopeAI
Scope develops AI-enabled software to accelerate industrial inspection workflows, from reporting to asset integrity, and works with leading TIC players to shorten field reporting to 12 minutes and onboard clients seven times faster.
Fazeshift
Fazeshift offers an AI-driven accounts receivable platform that automates AR processes, reduces manual work, and accelerates revenue cycles for large enterprises. Backed by Y Combinator, Gradient (Google’s AI venture arm), and founded by Ha
Nooks
Nooks is a platform that transforms sales reps from manual laborers to scientists by equipping teams with analytics. It grew from $0 to $5M ARR in two years, expanded 4x in 2023, led by Forbes 30 Under 30 founders.
Burnt
Burnt is building an AI brain for global supply chains, starting with the food sector; it already automates over $10M in monthly orders without humans, has raised $3.8M, and plans enterprise deployments across freight, manufacturing, and di
Paraform
Paraform is a recruiting marketplace that connects companies with a network of specialized recruiters to fill roles faster and more accurately. Backed by prominent investors and partners like Palantir and Decagon, it aims to be the first en
Tavus
Tavus is a human computing research lab and pioneer in human computing, building AI Humans to bridge the gap between people and machines and teach machines to be human. Founders Hassaan Raza and Quinn Favret lead Tavus, which is growing.
Unusual
Unusual defines Brand Engineering, a research field that measures how LLMs perceive brands and benchmarks brand performance against peers. Through applied interpretability and narrative-control experiments, it aims to let people shape their
Medra
Medra uses AI, robotics, and biology to accelerate life science research and eradicate disease, building a Scientific Physical AI platform to scale lab work and generate orders of magnitude more data for faster drug development and biology
AirOps
AirOps is the first end-to-end content engineering platform for marketing teams, helping brands get found and stay found in the AI era. With hubs in San Francisco, New York, and Montevideo, it serves marketers and is backed by prominent inv
Firebender
Firebender is an AI software company that develops AI coding assistance tools. Founded in 2024, it has raised $3.5 million in funding and currently has a team of three.
Synch
Synch, based in New York City, is the first AI-powered Salesforce system of engagement, backed by Y Combinator and executives from Retool, Ramp, and Superhuman. It enables enterprises to manage their Salesforce environment using natural-lan
HappyRobot
HappyRobot offers an AI-native operating system for real economy, starting with supply chains. It has raised $62M, including a $44M Series B in Sept 2025, from YC, Andreessen Horowitz, and Base10, led by Pablo and Javier Palafox and Luis Pa
Usul (YC S24)
Usul positions itself as the 'Amazon for Government,' enabling companies to sell to government quickly. With Fortune 500, U.S. Government, and NATO as customers and ARR near $5M, it is scaling a repeatable enterprise motion with internation
Conduit AI
Conduit builds AI-native conversational agents to automate high-touch business communications, focusing on hospitality and housing. It offers a help-desk platform for creating agents that handle text and voice conversations and escalate to
Zero Labs
At Zero develops a tax-forecasting engine with the goal of eliminating tax liabilities, positioning itself in the tax technology space.
Dataleap
Dataleap is the world's first vibe working platform, backed by $3 million in funding, aiming to be the first agentic work platform for tech-forward companies, with agents serving 2-person startups to 2,000-person unicorns; founders are Jan
Quander
Quander runs an applied AI product lab that automates invention, building thousands of inventions to improve humanity's future. It develops AI systems to discover, grow, and scale new ventures, driving venture creation through automated inv
Arphie
Arphie is building a platform for collaborative intelligence between go-to-market and product/engineering teams. Backed by top-tier VC firms and led by CEO/CTO co-founders who met at Harvard, it has posted rapid ARR growth since commerciali
Outset
Outset, a Y Combinator–backed startup, uses AI and ChatGPT to conduct in-depth qualitative interviews at scale, aiming to revolutionize qualitative research and deliver rich, scalable insights through innovative research tooling.
MangoDesk
Creates frontier data and environments to advance AI, bridging AI with the $5T knowledge-work economy and accelerating AI capabilities and adoption in knowledge work.
AthenaHQ
AthenaHQ provides an AI Search platform that helps global brands improve visibility, discoverability, and branding. It counts Coinbase, SoFi, and Twilio among its customers and serves over 200 clients with more than $2M ARR, underscoring ra
Cekura
Cekura is a Y Combinator–backed startup redefining AI voice agent reliability through testing and monitoring. Founded by IIT Bombay alumni with ETH Zurich credentials and high-stakes trading experience, it guarantees dependable performance,
Colare
Colare is an end-to-end hiring platform for hardtech teams in automotive, aerospace, energy, and defense. Its AI-powered simulations replicate real engineering workflows—from CAD to systems problem solving—to evaluate talent, with stack-ran
GovDash
GovDash enables businesses to win and deliver government contracts that advance American interests. Its customers won over $5B in government contracts in 2025, and GovDash has raised $42M in funding.
Poka Labs
Poka Labs, a San Francisco-based startup founded in 2023, builds AI agents that automate commercial operations for chemical manufacturers, led by Andrew Bass and Malay Shah; it is backed by Y Combinator, Flybridge, Pioneer Fund, and Beat Ve
Vantara
Vantara positions itself as an AI product engineer that monitors user sessions and feedback from support, sales, and channels, identifies patterns, prioritizes what to build, and enables PRs and A/B tests to close the loop between user inpu
Runway
Runway is a collaborative business planning platform that replaces spreadsheets with a modern planning solution, democratizing planning across the organization. Its customers include AngelList, Superhuman, ConvertKit, Lambda Labs, and Sandb
Scale AI
Scale AI provides data-centric infrastructure to accelerate AI development, helping organizations build strong AI models and derive business insights and operational efficiency; serving customers across tech, government, and enterprise, inc
Confident AI
Confident AI is the leading LLM evaluation platform behind the open-source DeepEval framework; its cloud product brings DeepEval to enterprises, backed by 600k+ monthly downloads, 5.3k+ GitHub stars, 40 million evaluations, and hundreds of
Opal Security
Opal provides enterprise identity and access management solutions. It is based in New York City and San Francisco and backed by Greylock, Battery Ventures, and Silicon Valley CISO Investments, serving hypergrowth startups and Fortune 500 co
TrueClaim
TrueClaim provides an AI-enabled platform for health plans, focused on advancing health-plan technology and modern operations.
Rulebase
Rulebase delivers visibility and confidence to modern support teams, helping them understand and improve the customer experience in real time. Its technology stack includes Python, React, and Electron JS.
