Healthcare startups in San Francisco

Assort Health

San Francisco

Assort Health offers what it calls the most comprehensive patient experience platform, handling 115M+ interactions since 2023 with 98%+ resolution, 99% scheduling accuracy, 4.4/5 patient satisfaction, and 15x revenue growth since Q4 2024, l

Counsel Health

San Francisco

Counsel is building an AI-driven healthcare practice to scale care delivery and provide rapid, personalized medical advice, leveraging partnerships with leading healthcare organizations and collaborative clinician–AI models; founded 2023, r

General Medicine

San Francisco

General Medicine is a healthcare store focused on transforming outpatient care access by providing fast, price-transparent guidance on the next best clinical steps for all patients, regardless of insurance, aiming to speed care and empower

Mandolin

San Francisco

Mandolin is building last-mile delivery infrastructure to speed development and delivery of cutting-edge drugs (cell/gene therapies, biologics), aiming to extend healthy lifespans by shortening time to patient access; backed by SignalFire,

Taxo AI

San Francisco

Taxo builds agents to automate administrative workflows in healthcare, reducing clinicians' administrative burden and enabling them to focus on patients. It provides workflow-support solutions for healthcare professionals to improve efficie

Onos Health

San Francisco

Onos Health is a San Francisco-based early-stage startup building an AI-powered platform to reduce waste in U.S. healthcare spending by aligning providers and payers, with a $6M seed round, live partnerships with major health plans, and exp

Roger Healthcare

San Francisco

Roger uses generative AI to alleviate staffing shortages in home health care, with full deployment at agencies serving tens of thousands of patients daily.

Radical Healthcare

San Francisco

Radical, a San Francisco-based company, aims to give every cancer patient access to the world’s best oncologist and holds exclusive access to a 400+ million-note, 8 million-record cancer dataset, backed by an elite advisory board and top-ti

Latent

San Francisco

Latent develops AI-driven medical intelligence software to optimize hospital and clinic workflows, speed medication access for patients, and boost provider revenues, collaborating with major healthcare systems to expand fast, affordable pro

Newton

San Francisco

Newton offers a next-generation AI phone system for dental organizations, targeting fast-growing dental groups to streamline patient communication and replace outdated phone systems and clunky tools, delivering unmatched visibility into the

Sapling

San Francisco

Sapling is building an operating system for independent private practices, starting with pediatrics and expanding to adult primary care, to help clinicians reclaim independence by automating the back-office and ultimately coordinating care.

New Lantern

San Francisco

New Lantern is a radiology software company delivering an AI-powered cloud platform to automate imaging workflows and replace on-premise radiology SaaS. It bills itself as the first AI-powered cloud radiology platform and engages radiologis

Evidently

San Francisco

Evidently is a Clinical Data Intelligence platform built on 12 years of advanced research in Machine Reading and Knowledge Graph, aiming to dramatically improve the efficiency and effectiveness of clinical data workflows.

Vitalize

San Francisco

Vitalize is building an operating system for hospital operations, starting with staffing and scheduling optimization. Backed by Y Combinator and leading health systems, it reached seven-figures in ARR in under six months.

Vitalize Care

San Francisco

Vitalize is building an operating system for hospital operations, starting with staffing and scheduling optimization. Backed by Y Combinator and leading health systems, it reached seven-figures in ARR in under six months.

Freshpaint

San Francisco

Freshpaint builds privacy infrastructure to safeguard patient privacy and help marketing teams promote access to healthcare; its core product, the Privacy Platform, automates HIPAA compliance for healthcare providers' websites and apps.

Modern Fertility

San Francisco

**At-home fertility test for women who aren't ready for kids right now…** We're a women’s health company making personalized reproductive health information more accessible, earlier in life. We make the same laboratory tests that were prev

Luminai

San Francisco

Luminai automates repetitive manual tasks in mission-critical business processes across insurance, healthcare, and financial services. San Francisco based since 2019, it has raised $20M and is led by Kesava Kirupa Dinakaran, noted for hacka

Codex Health

San Francisco

Codex is a mission-driven health technology company developing modern, powerful, and intuitive products to help healthcare providers deliver the best outcomes for patients.

Probably Genetic

San Francisco

Probably Genetic operates a data platform for drug developers and patient advocacy groups to identify undiagnosed patients, analyze disease state with ML and at-home testing, and enable early diagnoses, trials, and treatments for severe dis

Pair Team

San Francisco

Pair Team is a San Francisco-based startup, founded in 2019, serving the highest-need Medicaid recipients via a community-led, virtual care model, addressing housing instability and food access by partnering with shelters and safety-net pro

PicnicHealth

San Francisco

PicnicHealth makes medical records easily accessible and uses the data to power patient-centered, non-interventional clinical research, leveraging AI to advance data-powered studies.

SimplyInsured

San Francisco

SimplyInsured provides 100% online health insurance for small businesses, simplifying coverage procurement. Backed by Y Combinator and Silicon Valley investors, it aims to disrupt the $20B health insurance brokerage market and serves thousa

Invert

San Francisco

Invert Bio, a San Francisco-based biotech startup with 25 employees, aims to reduce the cost and time of using biology to manufacture almost everything. It operates in healthcare and industrial biology to accelerate biomanufacturing across

Triomics

San Francisco

Triomics provides an oncology-focused AI engine, OncoLLM, that reduces the burden of manual chart review for cancer care providers and accelerates clinical trial enrollment while powering quality improvement and strategic initiatives.

Resonate AI

San Francisco

An AI-driven platform that helps healthcare practices capture new patients by converting missed calls into patient inquiries, led by a founder with 10+ years of AI experience and five patents who previously built 0-to-1 ventures at Microsof

Scritch

San Francisco

Scritch is building the leading AI-powered operating system for veterinary care, providing AI agents to streamline operations for veterinary clinics, including scheduling and clinical workflows.

Syntra

San Francisco

Syntra operates in healthcare revenue cycle management, integrating with all major EHR systems. It processes hundreds of millions of dollars in charges annually and aims to increase revenue, reduce audit risk and denials, and shorten accoun

Attunement

San Francisco

Attunement, a YC W24 company, builds compliance infrastructure that connects clinical data pipelines, model outputs, and audit systems to make AI-assisted behavioral care traceable, explainable, and auditable. Clinics cut audit prep time by

Mochi Health

San Francisco

Mochi Health is building a personalized healthcare platform that connects patients to treatments, tools, and clinical support, combining virtual care, data-driven protocols, and compassionate providers to deliver scalable, technology-powere

General Proximity

San Francisco

**General Proximity** The next generation of induced-proximity medicines. Active biotech drug-discovery San Francisco **Founders** Armand Cognetta Founder Armand completed his PhD in Chemical Biology at the Scripps Research Institute un

Joon Health

San Francisco

Joon Health offers an integrated digital platform for pediatric behavior disorders (ADHD, autism, anxiety, depression), aiming to become the first-line digital treatment; since 2022 it has 20,000+ paying subscribers and over $6 million in f

Neon Health

San Francisco

Neon Health automates patient access workflows for pharma companies, streamlining benefit verifications, prior authorizations, financial assistance enrollment, onboarding, and adherence management to accelerate access to life-saving treatme

Sunflower

San Francisco

Sunflower is a seed-stage startup with a 10-person team pursuing sobriety for 1.2 billion people affected by addiction. Founders bring YC, Techstars, and Rupa Health experience, with past products delivering up to $75M/year and nine-figure

Sonia

San Francisco

San Francisco startup developing Sonia, a safe AI therapist designed to clinically match 99th percentile human therapist and broaden access to mental health care. A team has raised $3.5M from YC, Moonfire, Verkada, Reddit, Instacart founder

Orchid

San Francisco

Orchid (W23) is an AI-powered EHR for independent mental health professionals. Based in San Francisco, it has a four-person team and was founded by Joseph Pomianowski.

Penciled

San Francisco

Penciled is a healthcare tech company building an AI-driven patient engagement agent for physical therapists to automate time-consuming front-desk tasks; part of Y Combinator's Winter 2024 cohort and deployed across multiple PT chains natio

AgileMD

San Francisco

AgileMD develops a cloud-based hospital decision-support platform used by thousands of physicians across hospitals and clinics in the United States, headquartered in San Francisco, delivering care decisions grounded in current medical knowl

Egress Health

San Francisco

Egress Health automates dental insurance revenue cycle management, making accepting insurance as easy as cash by sending claims, tracking payments, and collecting reimbursements. It’s live at dozens of private clinics and groups and has a Y

Lamar Health

San Francisco

Lamar Health leverages data science and AI to scale staff expertise for specialty medication workflows and automate patient paperwork, building infrastructure that connects care teams, clinics, and patients.

Andy AI

San Francisco

Andy AI is a seed-stage startup automating clinical documentation for home-visit nurses by turning visit audio into completed forms, cutting the 90-minute process and improving care for older adults while addressing America's nursing shorta

Pairtu

San Francisco

Pairtu is a healthcare coordination platform connecting Medicare patients with dedicated advocates to navigate care and secure better outcomes, led by Harvard-educated entrepreneurs; it operates in a $60B market with million-dollar run-rate

Planbase

San Francisco

Planbase is a flexible AI-powered platform that embeds intelligence into operations, tailoring to each workflow to boost speed and accuracy; it serves healthcare organizations touching 100M+ patients, including $500M+ revenue leaders, with

Trellis AI

San Francisco

Trellis provides an AI agent that automates healthcare administrative workflows—such as intake, prior authorizations, and appeals—positioning itself as a solutions-focused partner to increase provider revenue while reducing administrative b

Novoflow

San Francisco

Novoflow deploys AI employees for medical clinics, building computer agents to modernize healthcare and automate front- and back-office tasks across a fragmented 400+ EHR ecosystem; contracts secured, backed by YC advisers and top investors

Medplum

San Francisco

Medplum is an open-source, API-first electronic health record (EHR) platform that increases access to and usefulness of medical data, used by major digital health and life sciences companies to build medical applications.

Finni Health

San Francisco

Finni Health enables autism care providers to start, run, and grow their own practice with a dedicated platform, backed by General Catalyst, Greymatter, and Y Combinator, as the market expands with rising diagnoses and enabling legislation.

Datrics

San Francisco

Datrics, a San Francisco-based company with 22 employees, develops generative AI for healthcare coding automation, led by CEO Anton Vaisburd and founded by Kirill Kirykov and Volodymyr Sofinskyi, both seasoned data science and analytics exe

Multiply Labs

San Francisco

Multiply Labs, a 36-person San Francisco-based company founded in 2016 by Fred Parietti and Alice Melocchi, delivers pharmaceutical automation via a pharma robotics as a service model, enabling life-saving therapies and partnering with glob

MDalgorithms

San Francisco

MDalgorithms is a remote, AI-driven dermatology and hair care company building custom deep learning models, native apps, and e-commerce APIs. It runs MDacne, a dermatology app with millions of downloads, and MDhair, a regrowth kit, backed b

Daybreak Health

San Francisco

Daybreak Health is a YC-backed provider of comprehensive online mental health care for youth and families aged 5–19. It partners with public school districts and insurers to cover costs and aims for zero-cost care and profitability by 2026.

Collectly

San Francisco

Collectly is a profitable healthcare tech startup that uses proprietary EHR interfaces to simplify billing, accelerate cash flow, and enhance the patient financial experience, serving 300k+ patients daily across U.S. practices with AI-drive

Clipboard

San Francisco

Clipboard connects workplaces with nearby professionals to turn extra time and ambition into career growth and financial opportunity. It is a Y Combinator W17 company founded by Wei Deng, a Yale and Yale Law School graduate.

Verge Genomics

San Francisco

Verge Genomics uses AI and human tissue data in its CONVERGE platform to map disease biology, identify targets, and de-risk drug development, with two drugs in clinical trials, 282 targets discovered, and partnerships worth $1.6B.

Sample

San Francisco

Sample Healthcare is a profitable San Francisco-based healthcare AI company backed by notable investors including Kulveer Taggar, Zack Kanter, Homebrew Ventures, Y Combinator, and alumni from Retool, Stripe, Ambience Healthcare, and Watersh

Readily

San Francisco

Readily provides AI-powered compliance tools for healthcare organizations, aiming to build the compliance layer for every company and cut admin costs. Founded by Edward Tiong and Wei An Wang, it serves large healthcare clients and reports 3

SafeBeat

San Francisco

SafeBeat Rx is a healthcare tech company developing ECG software and a take-home kit to enable at-home initiation of heart medications, backed by YC Summer 2021 and pursuing clinician-approved AI-driven dosing and faster FDA pathways to red

Toothy AI

San Francisco

Toothy AI automates back-office operations for dental clinics using large language models, led by founders with proven AI-enabled B2B track records (Chen’s SoftBank-backed $1M ARR AI email solution; Kerrigan’s pre-ChatGPT LLM campaign tool)

Bunkerhill Health

San Francisco

Bunkerhill Health translates AI algorithms from leading research institutions (Stanford, Harvard, Johns Hopkins) into clinical use, bridging academic innovation and patient care. It markets a scalable AI healthcare solution and invites cust

Rinse

San Francisco

Rinse is an early, well-funded startup building the One Medical for dental to redesign the dental industry from the ground up, backed by investors such as Y Combinator, Optum Ventures, PJC, Global Founders Capital, and Liquid 2, among other

Candid Health

San Francisco

Candid Health uses data science and machine learning to automate medical billing and reduce costs in the US healthcare system. A Y Combinator W20 alum with strong investor backing and rising demand from potential customers.

Apero Health

San Francisco

Apero is a San Francisco-based Y Combinator-backed startup simplifying medical billing with greater transparency; it has raised about $240 million from notable investors and serves 30+ practices, some with 50+ providers, while actively hiri