Software startups in San Francisco

Alembic

San Francisco

Alembic provides causation analytics on proprietary data at scale, answering questions generic AI cannot. It serves Fortune 500 clients including Nvidia, Delta Air Lines, Mars; it operates one of the world's fastest private supercomputers a

Textla

San Francisco

Textla democratizes SMS for businesses with a lowest-price guarantee, delivering hard-dollar/time savings, and grew from $0 to $13M in revenue in 18 months with under 50 employees.

Paradigm

San Francisco

Paradigm is a San Francisco-based AI-powered workspace focused on large-scale agent orchestration, backed by Y Combinator and founders from Dropbox, Intercom, Langchain, Redis, Behance, and Posthog.

Willow

San Francisco

Willow is building a voice operating system that enables computer control via voice, writes for you today, takes actions for you tomorrow, and anticipates needs before you ask. It has Uber adoption; backed by Y Combinator and Box Group.

GovDash

San Francisco

GovDash enables businesses to win and deliver government contracts that advance American interests. Its customers won over $5B in government contracts in 2025, and GovDash has raised $42M in funding.

Harmonic

San Francisco

Harmonic is a startup discovery engine that converts fragmented sources into structured knowledge about startups, investors, and people, mapping the ecosystem and helping the most promising founders get found and funded by the world's large

Standard Fleet

San Francisco

Standard Fleet develops next-generation fleet management software focused on electric vehicles and aims to become the default software layer for fleet operators, empowering them to maximize efficiency and profitability by unlocking the valu

CommodityAI

San Francisco

CommodityAI is a San Francisco-based AI company serving the commodities industry, founded by former commodity traders and operators with deep industry expertise. Backed by Y Combinator and Rebel Fund, it aims to build intelligence at the fo

Evidently

San Francisco

Evidently is a Clinical Data Intelligence platform built on 12 years of advanced research in Machine Reading and Knowledge Graph, aiming to dramatically improve the efficiency and effectiveness of clinical data workflows.

Meter

San Francisco

Meter is a vertically integrated infrastructure provider that builds its hardware, software, and operations to create scalable networks and reduce costs, backed by Sequoia, Sam Altman, and Lachy Groom, serving customers like Bridgewater, Ly

Envoy

San Francisco

Envoy Workplace, launched May 2023, is a platform for hybrid workplaces that safely connects and enables collaboration across 20,000+ locations, serving Slack, Pinterest, and Warby Parker; backed by Andreessen Horowitz, Menlo Ventures, Init

Dioxus Labs

San Francisco

Dioxus Labs develops cross-platform apps using Rust and maintains an open-source project competing with Flutter, React Native, and native toolkits. With nearly 20,000 GitHub stars and participation in the GitHub Accelerator, it has gained n

Numero

San Francisco

Numero builds fundraising software for political campaigns and nonprofits, aiming to reinvent fundraising. Since 2019 it serves thousands of clients—from races to US Senate—and has helped manage over $10 billion in contributions, backed by

Verse Medical

San Francisco

Verse Medical is a New York City-based health tech company that software-drives medical supply ordering and management for patients and clinics, serving hospitals nationwide and building software infrastructure to modernize medical-supply w

Capy

San Francisco

Scout is an AI-native software engineering agent that operates asynchronously on its own VM and tackles long-horizon tasks on large codebases.

Stably AI

San Francisco

Stably AI focuses on AI-powered QA testing to help teams deliver software faster. Founded by experts who built testing infrastructure at Google and ML systems at Uber, it positions itself as a leader in AI-powered QA testing.