
Two Sigma Ventures
65 portfolio companies · 12 on the map · $2.1B raised · 6 cities · twosigmaventures.com
Portfolio map
12 Two Sigma Ventures portfolio companies on the map.
Portfolio companies

Xaira Therapeutics
South San Francisco
an integrated biotechnology company driving advances in AI to transform how we treat disease.
Biotechnology Research$1BEst. 2023
Socure
San Francisco
Socure builds identity trust infrastructure to verify all good identities in real time and stop fraud before it starts. It serves financial services, government, gaming, healthcare, telecom, and e-commerce, with customers including Chime, S
SaaS$740MEst. 2012Hiring fast
Freeform
Los Angeles
Freeform builds AI-native manufacturing systems that unify software, hardware, and physics to produce industrial-scale parts at the speed of ideation, treating manufacturing as an integrated system to design, build, and scale complex hardwa
Automation Machinery Manufacturing$115MEst. 2019
Osmo
New York
Osmo develops scent-enabled computing to give computers a sense of smell, aiming to improve health and wellbeing and enhance health outcomes. It positions itself as a forward-looking technology player in wellbeing-focused innovation.
HealthTech$70M
NetBox Labs
New York
NetBox Labs is the company behind NetBox, the open-source Network Source of Truth that is the most popular in its category, developed by a large open-source community and featuring an extensive ecosystem of integrations into popular tooling
SaaS$55MEst. 2023
NewtonX
New York
NewtonX is an end-to-end B2B market research partner that answers tough questions via a proprietary network of verified professionals, delivering rapid, AI-enabled insights through its platform and dedicated business consultants to power mi
Marketing Services$47MEst. 2016
Highbeam
New York
Highbeam is a banking and cash management platform for goods sellers, founded by veterans of Shopify, Square, Rippling and Toast, turning banking into a profit center. It serves $1B+ GMV and gives $5M–$200M brands enterprise financial capab
FinTech$47MEst. 2021
Swarm Aero
Oxnard
Swarm Aero aims to build the world's largest UAV swarm and redefine air power for national security through unmanned aerial vehicle swarm development.
Aerospace and Defense$35MEst. 2022- X
Xilis
Durham
Xilis is an oncology and precision health company that provides technologies to diagnoses cancer.
Biotechnology$19.4MEst. 2019 Okteto
San Francisco
**Cloud Development Environments with one click** At Okteto, we are working hard at creating the next-generation development experience for teams of all sizes. Have you ever seen how long it takes a developer to set up everything they need
SaaS$18.1MEst. 2018
Comet
New York
Comet is an AI model evaluation platform backed by thousands of users and Fortune 100 companies, delivering insights and data to help build more accurate AI models while boosting productivity, collaboration, and visibility across teams.
AI/MLSeries BEst. 2017
Theorem
San Francisco
Theorem is an AI and programming languages research lab in San Francisco that develops scalable software correctness feedback and cryptography securing trillions of connections; it publishes at NeurIPS, ICML, POPL, and ITP, and runs educati
AI/ML
More portfolio companies
53 more Two Sigma Ventures investments we track beyond the map.
RadarBrooklyn · Series C
RemoteSan Francisco · Series C
Membrane LabsNew York · Series A
AnomaloPalo Alto · Series B
RiveSan Francisco · Series A
FlatfileDenver · Series B
NullifySan Francisco · Seed
SoraSan Francisco · Series A
SDFLos Angeles · Seed
Cajal NeuroscienceSeattle · Series A
Ansel HealthClaymont · Venture
Arda TherapeuticsSan Francisco · Series A
ReplicatedLos Angeles · Series C
CastorAmsterdam · Series B
CoverWalletNew York · Series B
Appia BioCulver City · Series A
CanaryNew York · Corporate
Enigma TechnologiesNew York · Series C
KasistoNew York · Series B
Exai BioPalo Alto · Series A
MioAustin · Seed
Isabl Inc.New York · Seed
CyleraNew York · Series A
AnkiSan Francisco · Series D
EntryPointNew York · Seed
Smartfrog GroupNew York · Venture
TinybopBrooklyn · Series A
Pyth NetworkZug · Venture
littleBits ElectronicsNew York · Series B
Risk LabsOttawa · Venture
RaincoatSan Juan · Seed
ObjectiveSan Francisco · Seed
Spruce UpSeattle · Seed
WristcamSan Mateo · Series B
Pro.comSeattle · Series B
Per DiemBrooklyn · Seed
InsightSquaredBoston · Series D
Boundless ImmigrationSeattle · Series C
Switchboard SoftwareSan Francisco · Seed
Rift FinanceNew York · Venture
Tiger Data (creators of TimescaleDB)New York · Series C
JuiceroSan Francisco · Series B
Bark TechnologiesCharlotte · Series B
SpellNew York · Series A
EndlessAIPalo Alto · Funding
C3 ExchangeGrand Cayman · Seed
FiredomeNew York · Series A
UMANew York · Venture
Amper MusicNew York · Seed
PlacedSeattle · Series B
Dynasty.comLos Angeles · Seed
DorsalSan Francisco · Seed
DextroNew York · Seed
Portfolio map
12 Two Sigma Ventures portfolio companies on the map.