Startups in San Mateo

194 companies · 115 open roles in San Mateo, United States.

By the Numbers

194Startups

115Open roles

View jobs →

$2.5BTotal funding raised

33Companies hiring

$48MMedian funding

Funding

Series A 41Series B 28Series C 21Seed Round 30Venture Round 15

Industries

Software Development 9 SaaS 8 AI/ML 4 Technology, Information and Internet 4 Enterprise Software 3 Generative AI 3 ai 3 IT Services and IT Consulting 3 MarTech 2 B2B 2

Roles

Featured

Leading startups in San Mateo

WisdomAI

San Mateo

$73M

WisdomAI provides data insights to every employee, leveraging Generative AI. As an early-stage company with Fortune100 paying customers, it is positioned to shape its product and engineering roadmap.

Data Infrastructure and AnalyticsEst. 2023

GC AI

San Mateo

$71.6M

The AI for in-house counsel

Technology, Information and InternetEst. 2023Hiring fast

Archetype AI

San Mateo

$48M

Archetype AI develops Physical AI agents that harness real-world sensor data to enhance decision-making and automate processes.

Technology, Information and InternetEst. 2023

Now hiring

115 open roles at San Mateo startups

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Software Development, SaaS, AI/ML & more

191 startups

Tofu

San Mateo

Tofu is an early-stage generative AI startup based in San Mateo, CA, backed by Index Ventures and SignalFire; it aims to build a unified platform for hyper-personalized, omnichannel B2B marketing campaigns at scale for mid-market and enterp

AI/ML$17MEst. 2023

Zaimler.ai

San Mateo

Zaimler is building an AI-based data platform that shifts beyond traditional databases toward question-driven data interaction, enabling AI agents to retrieve, understand, and utilize information. With a lean 12-person team and proven found

Data Infrastructure and Analytics$10MEst. 2024

Maxima

San Mateo

Maxima maximizes shareholder value by making financial information accessible, accurate, and actionable, addressing fragmented data and missing forward-looking ROI insights, with a moonshot to close books on day zero and enable continuous c

AI/ML$10MEst. 2024

Skywalk AI

San Mateo

Skywalk develops voice AI to enable more natural interactions with technology and intuitive access to the digital world. Its founding team brings deep expertise in machine learning, voice recognition, and hardware, with experience serving F

AI/ML$4.5MEst. 2024

Besimple AI

San Mateo

Besimple AI builds a data flywheel that enables continuous model improvement and monitoring through human-in-the-loop, serving AI teams of all sizes and budgets.

AI/ML$3MEst. 2025

Slate Technologies

San Mateo

Slate Technologies is a AI driven digital enabler platform for the construction industry.

Software Development$20.2MEst. 2020

VESSL

San Mateo

Founded in Seoul, the company is expanding to the United States after a $12 million Series A, with about 40 employees and backing from top-tier Korean investors. It serves AI-native startups, research labs, and enterprises, supporting AI in

AI/ML$12.2MEst. 2020

Remotebase

San Mateo

Remotebase hires, trains, and places local software engineers.

IT Services and IT Consulting$3.5MEst. 2020

Firework

San Mateo

Firework is powered by enterprise-grade infrastructure designed to scale personalized video experiences and agentic shopping journeys across digital commerce.

Marketing Services$269.3MEst. 2017

Notable

San Mateo

Notable is the AI platform for healthcare operations.

Software Development$119.2MEst. 2017

TrustLab

San Mateo

TrustLab is an AI software company used to protect against misinformation, hate speech, identity fraud, and other harmful content.

Software Development$15MEst. 2019

Veryfi

San Mateo

Veryfi is an AI-based platform that converts unstructured business documents into structured data, trusted by enterprises. It has raised $12 million from investors including NewView Capital, Act One Ventures, TI Platform, Y Combinator and Z

FinTech$12MEst. 2017

San Mateo snapshot

Software Development leads with 194+ startups

$2.5BTotal Raised

Luminary Cloud

San Mateo

Luminary is a Physics AI platform for rapid design iteration, design exploration and optimization of physical products.

Software Development$187M

SnapLogic

San Mateo

SnapLogic is a software company that provides a platform for enterprise cloud and big data integration.

Software Development$371.3MEst. 2006

Cala Health

San Mateo

Cala Health is a bioelectronic medicine company that develops wearable neuromodulation devices for the treatment of chronic diseases.

Medical Equipment Manufacturing$298.3MEst. 2014

Booster Fuels

San Mateo

Booster is a fleet management company that specializes in delivering renewable fuels, gasoline, diesel, and bio-diesel delivery services.

Truck Transportation$213.6MEst. 2014

Sendbird

San Mateo

Sendbird, based in California, provides messaging solutions for apps, handling over 7 billion conversations per month for 4,000+ apps including DoorDash and Yahoo Sports. Backed by ICONIQ, SoftBank, Tiger Global, and Y Combinator, it is a l

SaaS$168MEst. 2013

Salma Health

San Mateo

Right treatment. Right time.

Mental Health Care$80M

Bridgepointe Technologies

San Mateo

Bridgepointe is a technology advisory firm that assists in bridging the gap between technological investments and business objectives.

IT Services and IT Consulting$100MEst. 2002

Murata America

San Mateo

Resonant is a development-stage company creating filter designs for radio frequency and front-ends for the mobile device industry.

Semiconductor Manufacturing$87.9MEst. 2012Hiring fast

B-Stock

San Mateo

B-Stock Solutions offers liquidation sales management solutions for companies.

Software Development$73.2MEst. 2008

Narvar

San Mateo

Narvar is the #1 platform for intelligent personalization “beyond buy,” trusted by 1,500+ of the world’s most admired brands—including Sephora, Levi’s, Sonos, Warby Parker, and LVMH.

Technology, Information and Internet$64MEst. 2012

Openprise

San Mateo

Openprise provides a RevOps data automation cloud, assisting businesses in converting their data into actionable insights.

Software Development$58.3MEst. 2014

Netomi

San Mateo

Netomi AI delivers AI-driven, brand-safe customer engagement and Self-Driving Customer Care for the world's largest brands, claiming a leading role in the Generative AI revolution; backed by Y Combinator, Index Ventures, Jeffrey Katzenberg,

AI/ML$30MEst. 2015

Guidewire Software

San Mateo

Guidewire Software provides core back-end systems software to the global property, casual and worker's compensation insurance industry.

Software Development$30MEst. 2001Hiring fast

OPYA

San Mateo

Opya transforms autism care by successfully connecting treatment with technology.

Health, Wellness & Fitness$19.3MEst. 2015

Backblaze External Website

San Mateo

Backblaze provides high-performance, secure cloud object storage for AI/ML, SaaS, and digital media workloads, serving over 500,000 customers in 175+ countries. Headquartered in San Mateo, California, it is publicly traded on Nasdaq under B

Data Infrastructure and Analytics$5MEst. 2007

Dyneti Technologies

San Mateo

Dyneti is building authentication tech to make digital payments seamless and secure. It has raised $2.2M from Shasta Ventures, Y Combinator, and angels; processes hundreds of millions of card scans for Fortune 100s and unicorns, via mobile

FinTech$2.2MEst. 2018

ZOLA iNTELLIGENCE

San Mateo

Pioneering the world’s first enterprise technology platform purpose-built for energy access markets.

Technology, Information and InternetEst. 2023

Jupiter Intelligence

San Mateo

Jupiter offers climate risk analytics that turns sophisticated climate science into actionable data.

Climate Data and AnalyticsSeries CEst. 2017

Manticore Games

San Mateo

Manticore Games develops Core, a platform to build, share, and play online games.

Computer GamesSeries CEst. 2016

OneSignal

San Mateo

OneSignal began as a developer-friendly push notification API and has grown into omnichannel customer engagement platform, serving 1.8 million marketers, developers, and 1 million businesses, delivering 12 billion messages daily across 140

SaaSSeries CEst. 2011

Roblox

San Mateo

Roblox's vision is to reimagine the way people come together.

Software DevelopmentEst. 2004Hiring fast

Blameless

San Mateo

Blameless offers the only complete reliability engineering platform that brings together AI-driven incident resolution, blameless retrospectives, SLOs/Error Budgets, and reliability insights reports and dashboards,…

IT Services and IT ConsultingSeries B